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Electrostatic forces as dominant interactions between proteins and polyanions: an ESI-MS study of fibroblast growth factor binding to heparin oligomers
The interactions between fibroblast growth factors (FGFs) and their receptors (FGFRs) are facilitated by heparan sulfate (HS) and heparin (Hp), highly sulfated biological polyelectrolytes. The molecular basis of FGF interactions with these polyelectrolytes is highly complex due to the structural het...
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| Pubblicato in: | J Am Soc Mass Spectrom |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5808462/ https://ncbi.nlm.nih.gov/pubmed/28211013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1596-0 |
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