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Dissecting Dynamic and Hydration Contributions to Sequence-Dependent DNA Minor Groove Recognition
Sequence selectivity is a critical attribute of DNA-binding ligands and underlines the need for detailed molecular descriptions of binding in representative sequence contexts. We investigated the binding and volumetric properties of DB1976, a model bis(benzimidazole)-selenophene diamidine compound w...
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| Veröffentlicht in: | Biophys J |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567977/ https://ncbi.nlm.nih.gov/pubmed/32898478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.08.013 |
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