Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry

Protein–DNA interactions are key to the functionality and stability of the genome. Identification and mapping of protein–DNA interaction interfaces and sites is crucial for understanding DNA-dependent processes. Here, we present a workflow that allows mass spectrometric (MS) identification of protei...

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Udgivet i:Nat Commun
Main Authors: Stützer, Alexandra, Welp, Luisa M., Raabe, Monika, Sachsenberg, Timo, Kappert, Christin, Wulf, Alexander, Lau, Andy M., David, Stefan-Sebastian, Chernev, Aleksandar, Kramer, Katharina, Politis, Argyris, Kohlbacher, Oliver, Fischle, Wolfgang, Urlaub, Henning
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567871/
https://ncbi.nlm.nih.gov/pubmed/33067435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19047-7
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