Deuteros 2.0: peptide-level significance testing of data from hydrogen deuterium exchange mass spectrometry

SUMMARY: Hydrogen deuterium exchange mass spectrometry (HDX-MS) is becoming increasing routine for monitoring changes in the structural dynamics of proteins. Differential HDX-MS allows comparison of protein states, such as in the absence or presence of a ligand. This can be used to attribute changes...

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Gepubliceerd in:Bioinformatics
Hoofdauteurs: Lau, Andy M, Claesen, Jürgen, Hansen, Kjetil, Politis, Argyris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055227/
https://ncbi.nlm.nih.gov/pubmed/32722756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa677
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