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Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins

RNA–protein complexes play pivotal roles in many central biological processes. While methods based on next-generation sequencing have profoundly advanced our ability to identify the specific RNAs bound by a particular protein, there is a dire need for precise and systematic ways to identify RNA inte...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Kramer, Katharina, Sachsenberg, Timo, Beckmann, Benedikt M., Qamar, Saadia, Boon, Kum-Loong, Hentze, Matthias W., Kohlbacher, Oliver, Urlaub, Henning
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485471/
https://ncbi.nlm.nih.gov/pubmed/25173706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3092
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