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Synthesis and Inhibitory Studies of Phosphonic Acid Analogues of Homophenylalanine and Phenylalanine towards Alanyl Aminopeptidases

A library of novel phosphonic acid analogues of homophenylalanine and phenylalanine, containing fluorine and bromine atoms in the phenyl ring, have been synthesized. Their inhibitory properties against two important alanine aminopeptidases, of human (hAPN, CD13) and porcine (pAPN) origin, were evalu...

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Bibliografiset tiedot
Julkaisussa:Biomolecules
Päätekijät: Wanat, Weronika, Talma, Michał, Dziuk, Błażej, Kafarski, Paweł
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565091/
https://ncbi.nlm.nih.gov/pubmed/32938014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091319
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