A Methylidene Group in the Phosphonic Acid Analogue of Phenylalanine Reverses the Enantiopreference of Binding to Phenylalanine Ammonia‐Lyases

Aromatic amino acid ammonia‐lyases and aromatic amino acid 2,3‐aminomutases contain the post‐translationally formed prosthetic 3,5‐dihydro‐4‐methylidene‐5H‐imidazol‐5‐one (MIO) group. MIO enzymes catalyze the stereoselective synthesis of α‐ or β‐amino acid enantiomers, making these chemical processe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Adv Synth Catal
Prif Awduron: Bata, Zsófia, Qian, Renzhe, Roller, Alexander, Horak, Jeannie, Bencze, László Csaba, Paizs, Csaba, Hammerschmidt, Friedrich, Vértessy, Beáta G., Poppe, László
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Full Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573973/
https://ncbi.nlm.nih.gov/pubmed/28919846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201700428
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg