A Methylidene Group in the Phosphonic Acid Analogue of Phenylalanine Reverses the Enantiopreference of Binding to Phenylalanine Ammonia‐Lyases

Aromatic amino acid ammonia‐lyases and aromatic amino acid 2,3‐aminomutases contain the post‐translationally formed prosthetic 3,5‐dihydro‐4‐methylidene‐5H‐imidazol‐5‐one (MIO) group. MIO enzymes catalyze the stereoselective synthesis of α‐ or β‐amino acid enantiomers, making these chemical processe...

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Dettagli Bibliografici
Pubblicato in:Adv Synth Catal
Autori principali: Bata, Zsófia, Qian, Renzhe, Roller, Alexander, Horak, Jeannie, Bencze, László Csaba, Paizs, Csaba, Hammerschmidt, Friedrich, Vértessy, Beáta G., Poppe, László
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573973/
https://ncbi.nlm.nih.gov/pubmed/28919846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201700428
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