A Methylidene Group in the Phosphonic Acid Analogue of Phenylalanine Reverses the Enantiopreference of Binding to Phenylalanine Ammonia‐Lyases

Aromatic amino acid ammonia‐lyases and aromatic amino acid 2,3‐aminomutases contain the post‐translationally formed prosthetic 3,5‐dihydro‐4‐methylidene‐5H‐imidazol‐5‐one (MIO) group. MIO enzymes catalyze the stereoselective synthesis of α‐ or β‐amino acid enantiomers, making these chemical processe...

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Bibliografski detalji
Izdano u:Adv Synth Catal
Glavni autori: Bata, Zsófia, Qian, Renzhe, Roller, Alexander, Horak, Jeannie, Bencze, László Csaba, Paizs, Csaba, Hammerschmidt, Friedrich, Vértessy, Beáta G., Poppe, László
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
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Full Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573973/
https://ncbi.nlm.nih.gov/pubmed/28919846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201700428
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