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Synthesis and Inhibitory Studies of Phosphonic Acid Analogues of Homophenylalanine and Phenylalanine towards Alanyl Aminopeptidases

A library of novel phosphonic acid analogues of homophenylalanine and phenylalanine, containing fluorine and bromine atoms in the phenyl ring, have been synthesized. Their inhibitory properties against two important alanine aminopeptidases, of human (hAPN, CD13) and porcine (pAPN) origin, were evalu...

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Vydáno v:Biomolecules
Hlavní autoři: Wanat, Weronika, Talma, Michał, Dziuk, Błażej, Kafarski, Paweł
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565091/
https://ncbi.nlm.nih.gov/pubmed/32938014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091319
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