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Synthesis and Inhibitory Studies of Phosphonic Acid Analogues of Homophenylalanine and Phenylalanine towards Alanyl Aminopeptidases

A library of novel phosphonic acid analogues of homophenylalanine and phenylalanine, containing fluorine and bromine atoms in the phenyl ring, have been synthesized. Their inhibitory properties against two important alanine aminopeptidases, of human (hAPN, CD13) and porcine (pAPN) origin, were evalu...

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Библиографические подробности
Опубликовано в: :Biomolecules
Главные авторы: Wanat, Weronika, Talma, Michał, Dziuk, Błażej, Kafarski, Paweł
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565091/
https://ncbi.nlm.nih.gov/pubmed/32938014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091319
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