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Ras, PI3K and mTORC2 – three's a crowd?

The Ras oncogene is notoriously difficult to target with specific therapeutics. Consequently, there is interest to better understand the Ras signaling pathways to identify potential targetable effectors. Recently, the mechanistic target of rapamycin complex 2 (mTORC2) was identified as an evolutiona...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Smith, Stephen F., Collins, Shannon E., Charest, Pascale G.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561475/
https://ncbi.nlm.nih.gov/pubmed/33033115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.234930
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