A carregar...

Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP

An enhanced capacity for de novo lipid synthesis is a metabolic feature of most cancer cells that distinguishes them from their cells of origin. However, the mechanisms through which oncogenes alter lipid metabolism are poorly understood. We find that expression of oncogenic PI3K (H1047R) or K-Ras (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Ricoult, Stéphane J. H., Yecies, Jessica L., Ben-Sahra, Issam, Manning, Brendan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666838/
https://ncbi.nlm.nih.gov/pubmed/26028026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.179
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!