Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

The influence of 3D microenvironments on apoptosis susceptibility remains poorly understood. Here, we studied the susceptibility of cancer cell spheroids, grown to the size of micrometastases, to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Interestingly, pronounced, spatially co...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Differ
Päätekijät: Stöhr, Daniela, Schmid, Jens O., Beigl, Tobias B., Mack, Alexandra, Maichl, Daniela S., Cao, Kai, Budai, Beate, Fullstone, Gavin, Kontermann, Roland E., Mürdter, Thomas E., Tait, Stephen W. G., Hagenlocher, Cathrin, Pollak, Nadine, Scheurich, Peter, Rehm, Markus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560834/
https://ncbi.nlm.nih.gov/pubmed/32433558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0559-3
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia