CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants

To combine the CD27 stimulation inhibitory effect of blocking CD70 antibodies with an antibody-dependent cellular cytotoxicity (ADCC)-independent, cell death-inducing activity for targeting of CD70-expressing tumors, we evaluated here fusion proteins of the apoptosis-inducing TNF family member TRAIL...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Trebing, J, El-Mesery, M, Schäfer, V, Weisenberger, D, Siegmund, D, Silence, K, Wajant, H
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040681/
https://ncbi.nlm.nih.gov/pubmed/24481449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.555
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items