CD40-directed scFv-TRAIL fusion proteins induce CD40-restricted tumor cell death and activate dendritic cells

Targeted cancer therapy concepts often aim at the induction of adjuvant antitumor immunity or stimulation of tumor cell apoptosis. There is further evidence that combined application of immune stimulating and tumor apoptosis-inducing compounds elicits a synergistic antitumor effect. Here, we describ...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: El-Mesery, M, Trebing, J, Schäfer, V, Weisenberger, D, Siegmund, D, Wajant, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2013
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847307/
https://ncbi.nlm.nih.gov/pubmed/24232092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.402
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