Stress-induced TRAILR2 expression overcomes TRAIL resistance in cancer cell spheroids

The influence of 3D microenvironments on apoptosis susceptibility remains poorly understood. Here, we studied the susceptibility of cancer cell spheroids, grown to the size of micrometastases, to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Interestingly, pronounced, spatially co...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Death Differ
Главные авторы: Stöhr, Daniela, Schmid, Jens O., Beigl, Tobias B., Mack, Alexandra, Maichl, Daniela S., Cao, Kai, Budai, Beate, Fullstone, Gavin, Kontermann, Roland E., Mürdter, Thomas E., Tait, Stephen W. G., Hagenlocher, Cathrin, Pollak, Nadine, Scheurich, Peter, Rehm, Markus
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560834/
https://ncbi.nlm.nih.gov/pubmed/32433558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0559-3
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы