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Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex

Necroptosis is a form of regulated cell death caused by formation of the necrosome complex. However, the factors modulating this process and the systemic pathophysiological effects of necroptosis are yet to be understood. Here, we identified that Beclin 1 functions as an anti-necroptosis factor by b...

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Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Seo, Jinho, Seong, Daehyeon, Nam, Young Woo, Hwang, Chi Hyun, Lee, Seung Ri, Lee, Choong-Sil, Jin, Young, Lee, Han-Woong, Oh, Doo-Byoung, Vandenabeele, Peter, Song, Jaewhan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560833/
https://ncbi.nlm.nih.gov/pubmed/32457484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0561-9
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