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An outline of necrosome triggers

Necroptosis was initially identified as a backup cell death program when apoptosis is blocked. However, it is now recognized as a cellular defense mechanism against infections and is presumed to be a detrimental factor in several pathologies driven by cell death. Necroptosis is a prototypic form of...

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Bibliographic Details
Published in:Cell Mol Life Sci
Main Authors: Vanden Berghe, Tom, Hassannia, Behrouz, Vandenabeele, Peter
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887535/
https://ncbi.nlm.nih.gov/pubmed/27052312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2189-y
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