Yüklüyor......

Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis

Necroptotic signaling converges in the assembly of a cytosolic signaling platform, the necrosome, with the activation of its downstream effector, MLKL. RIPK1 and RIPK3, key components of the necrosome, act as signaling intermediates for the activation of MLKL. We report that RIPK3 and MLKL continuou...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Commun Biol
Asıl Yazarlar: Weber, Kathrin, Roelandt, Ria, Bruggeman, Inge, Estornes, Yann, Vandenabeele, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123744/
https://ncbi.nlm.nih.gov/pubmed/30271893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-017-0007-1
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!