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Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown

The delivery of small interfering RNAs (siRNA) is an efficient method for gene silencing through the induction of RNA interference (RNAi). It critically relies, however, on efficient vehicles for siRNA formulation, for transfection in vitro as well as for their potential use in vivo. While polyethyl...

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Bibliografiska uppgifter
I publikationen:Nanomaterials (Basel)
Huvudupphovsmän: Noske, Sandra, Karimov, Michael, Aigner, Achim, Ewe, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7557430/
https://ncbi.nlm.nih.gov/pubmed/32927826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10091809
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