Targeted Delivery of siRNA to Activated T Cells via Transferrin-Polyethylenimine (Tf-PEI) as a Potential Therapy of Asthma

Asthma is a worldwide health problem. Activated T cells (ATCs) in the lung, particularly T helper 2 cells (Th(2)), are strongly associated with inducing airway inflammatory responses and chemoattraction of inflammatory cells in asthma. Small interfering RNA (siRNA) as a promising anti-sense molecule...

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Publicado no:J Control Release
Main Authors: Xie, Yuran, Kim, Na Hyung, Nadithe, Venkatareddy, Schalk, Dana, Thakur, Archana, Kılıç, Ayşe, Lum, Lawrence G., Bassett, David JP, Merkel, Olivia M
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886848/
https://ncbi.nlm.nih.gov/pubmed/27001893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.03.029
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