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Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine

The use of small interference RNA (siRNA) to target oncogenes is a promising treatment approach for cancer. However, siRNA cancer therapies are hindered by poor delivery of siRNA to cancer cells. Transferrin receptor (TfR) is overexpressed in many types of tumor cells and therefore is a potential ta...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Xie, Yuran, Killinger, Bryan, Moszczynska, Anna, Merkel, Olivia M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273023/
https://ncbi.nlm.nih.gov/pubmed/27735873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101334
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