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Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine

The use of small interference RNA (siRNA) to target oncogenes is a promising treatment approach for cancer. However, siRNA cancer therapies are hindered by poor delivery of siRNA to cancer cells. Transferrin receptor (TfR) is overexpressed in many types of tumor cells and therefore is a potential ta...

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Publicat a:Molecules
Autors principals: Xie, Yuran, Killinger, Bryan, Moszczynska, Anna, Merkel, Olivia M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273023/
https://ncbi.nlm.nih.gov/pubmed/27735873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21101334
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