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Polymeric Nanoparticles Based on Tyrosine-Modified, Low Molecular Weight Polyethylenimines for siRNA Delivery

A major hurdle for exploring RNA interference (RNAi) in a therapeutic setting is still the issue of in vivo delivery of small RNA molecules (siRNAs). The chemical modification of polyethylenimines (PEIs) offers a particularly attractive avenue towards the development of more efficient non-viral deli...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Ewe, Alexander, Noske, Sandra, Karimov, Michael, Aigner, Achim
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920781/
https://ncbi.nlm.nih.gov/pubmed/31726756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110600
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