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Covalent protein display on Hepatitis B core-like particles in plants through the in vivo use of the SpyTag/SpyCatcher system

Virus-like particles (VLPs) can be used as nano-carriers and antigen-display systems in vaccine development and therapeutic applications. Conjugation of peptides or whole proteins to VLPs can be achieved using different methods such as the SpyTag/SpyCatcher system. Here we investigate the conjugatio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Peyret, Hadrien, Ponndorf, Daniel, Meshcheriakova, Yulia, Richardson, Jake, Lomonossoff, George P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555512/
https://ncbi.nlm.nih.gov/pubmed/33051543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74105-w
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