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Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2′-Deoxyuridine and 5-Bromo-2′-Deoxyurdine to Mammalian Cells

BrdU (bromodeoxyuridine) and EdU (ethynyldeoxyuridine) have been largely utilized as the means of monitoring DNA replication and cellular division. Although BrdU induces gene and chromosomal mutations and induces sensitization to photons, EdU‘s effects have not been extensively studied yet. Therefor...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Haskins, Jeremy S., Su, Cathy, Maeda, Junko, Walsh, Kade D., Haskins, Alexis H., Allum, Allison J., Froning, Coral E., Kato, Takamitsu A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555307/
https://ncbi.nlm.nih.gov/pubmed/32927807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186631
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