Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2′-Deoxyuridine and 5-Bromo-2′-Deoxyurdine to Mammalian Cells

BrdU (bromodeoxyuridine) and EdU (ethynyldeoxyuridine) have been largely utilized as the means of monitoring DNA replication and cellular division. Although BrdU induces gene and chromosomal mutations and induces sensitization to photons, EdU‘s effects have not been extensively studied yet. Therefor...

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Publicado en:Int J Mol Sci
Autores principales: Haskins, Jeremy S., Su, Cathy, Maeda, Junko, Walsh, Kade D., Haskins, Alexis H., Allum, Allison J., Froning, Coral E., Kato, Takamitsu A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555307/
https://ncbi.nlm.nih.gov/pubmed/32927807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186631
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