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Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2′-deoxyuridine and 5-ethynyl-2′-deoxycytidine

5-Ethynyl-2′-deoxyuridine (EdU) and 5-ethynyl-2′-deoxycytidine (EdC) are mainly used as markers of cellular replicational activity. Although EdU is employed as a replicational marker more frequently than EdC, its cytotoxicity is commonly much higher than the toxicity of EdC. To reveal the reason of...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Ligasová, Anna, Liboska, Radek, Friedecký, David, Mičová, Kateřina, Adam, Tomáš, Oždian, Tomáš, Rosenberg, Ivan, Koberna, Karel
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736823/
https://ncbi.nlm.nih.gov/pubmed/26740587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150172
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