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Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2′-Deoxyuridine and 5-Bromo-2′-Deoxyurdine to Mammalian Cells

BrdU (bromodeoxyuridine) and EdU (ethynyldeoxyuridine) have been largely utilized as the means of monitoring DNA replication and cellular division. Although BrdU induces gene and chromosomal mutations and induces sensitization to photons, EdU‘s effects have not been extensively studied yet. Therefor...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Haskins, Jeremy S., Su, Cathy, Maeda, Junko, Walsh, Kade D., Haskins, Alexis H., Allum, Allison J., Froning, Coral E., Kato, Takamitsu A.
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7555307/
https://ncbi.nlm.nih.gov/pubmed/32927807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186631
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