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Fingolimod (FTY720) Preserves High Energy Phosphates and Improves Cardiac Function in Heterotopic Heart Transplantation Model

During heart transplantation, donor heart leads to reduced oxygen supply resulting in low level of high energy phosphate (HEP) reserves in cardiomyocyte. Lower HEP is one of the underlying reasons of cell death due to ischemia. In this study we investigated the role of Fingolimod (FTY720) in heart t...

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Publicat a:Int J Mol Sci
Autors principals: Ahmed, Naseer, Farooq, Javeria, Sadiq, Soban, Meo, Sultan Ayoub, Jan, Azam, Cheema, Faisal H., Faggian, Giuseppe, Rungatscher, Alessio
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554839/
https://ncbi.nlm.nih.gov/pubmed/32911595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186548
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