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Fingolimod (FTY720) Preserves High Energy Phosphates and Improves Cardiac Function in Heterotopic Heart Transplantation Model

During heart transplantation, donor heart leads to reduced oxygen supply resulting in low level of high energy phosphate (HEP) reserves in cardiomyocyte. Lower HEP is one of the underlying reasons of cell death due to ischemia. In this study we investigated the role of Fingolimod (FTY720) in heart t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ahmed, Naseer, Farooq, Javeria, Sadiq, Soban, Meo, Sultan Ayoub, Jan, Azam, Cheema, Faisal H., Faggian, Giuseppe, Rungatscher, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554839/
https://ncbi.nlm.nih.gov/pubmed/32911595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21186548
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