Sphingosine 1-Phosphate Receptor Modulator Fingolimod (FTY720) Attenuates Myocardial Fibrosis in Post-heterotopic Heart Transplantation

Background and Objective: Sphingosine 1-phosphate (S1P), and S1P receptor modulator fingolimod have been suggested to play important cardioprotective role in animal models of myocardial ischemia/reperfusion injuries. To understand the cardioprotective function of S1P and its mechanism in vivo, we an...

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Publicat a:Front Pharmacol
Autors principals: Ahmed, Naseer, Linardi, Daniele, Muhammad, Nazeer, Chiamulera, Cristiano, Fumagalli, Guido, Biagio, Livio San, Gebrie, Mebratu A., Aslam, Muhammad, Luciani, Giovanni Battista, Faggian, Giuseppe, Rungatscher, Alessio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605636/
https://ncbi.nlm.nih.gov/pubmed/28966593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00645
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