A non–GPCR-binding partner interacts with a novel surface on β-arrestin1 to mediate GPCR signaling

The multifaceted adaptor protein β-arr1 (β-arrestin1) promotes activation of focal adhesion kinase (FAK) by the chemokine receptor CXCR4, facilitating chemotaxis. This function of β-arr1 requires the assistance of the adaptor protein STAM1 (signal-transducing adaptor molecule 1) because disruption o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Zhuo, Ya, Gurevich, Vsevolod V., Vishnivetskiy, Sergey A., Klug, Candice S., Marchese, Adriano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549033/
https://ncbi.nlm.nih.gov/pubmed/32753481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015074
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