TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition

Cancer stem cells (CSCs) have an established role in cancer progression and therapeutic resistance. The p63 proteins are important transcription factors which belong to the p53 family, but their function and mechanism in CSCs remain elusive. Here, we investigated the role of TAp63α in colorectal CSC...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Chen, Yue, Wang, Meng-huan, Zhu, Jian-yun, Xie, Chun-feng, Li, Xiao-ting, Wu, Jie-shu, Geng, Shan-shan, Han, Hong-yu, Zhong, Cai-yun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548006/
https://ncbi.nlm.nih.gov/pubmed/33040081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00273-z
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker