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TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition
Cancer stem cells (CSCs) have an established role in cancer progression and therapeutic resistance. The p63 proteins are important transcription factors which belong to the p53 family, but their function and mechanism in CSCs remain elusive. Here, we investigated the role of TAp63α in colorectal CSC...
Shranjeno v:
| izdano v: | Oncogenesis |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7548006/ https://ncbi.nlm.nih.gov/pubmed/33040081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00273-z |
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