Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis

Background: Tobacco smoke (TS) critically contributes to the development of lung cancer; however, the underlying molecular mechanisms remain unclear. The induction of cancer stem cells (CSCs) by TS represents an early event in tumor initiation. The lung cancer-related gene ΔNp63α is highly expressed...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Xie, Chunfeng, Zhu, Jianyun, Jiang, Ye, Chen, Jiaqi, Wang, Xueqi, Geng, Shanshan, Wu, Jieshu, Zhong, Caiyun, Li, Xiaoting, Meng, Zili
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643434/
https://ncbi.nlm.nih.gov/pubmed/31367260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33812
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