Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice

The transcription factor Ets1 is expressed at low levels in epidermal keratinocytes under physiological conditions, but is over-expressed in cutaneous squamous cell carcinoma (SCC). We previously showed that over-expression of Ets1 in differentiated keratinocytes of the skin leads to significant pro...

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Hlavní autoři: Chin, Shu Shien, Romano, Rose-Anne, Nagarajan, Priyadharsini, Sinha, Satrajit, Garrett-Sinha, Lee Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863418/
https://ncbi.nlm.nih.gov/pubmed/24337118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135397
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