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Successive Immunization With Epitope-Decreasing Dengue Antigens Induced Conservative Anti-Dengue Immune Responses

Repeated homologous antigen immunization has been hypothesized to hinder antibody diversification, whereas sequential immunization with heterologous immunogens can educate B cell differentiations towards conserved residues thereby facilitating the generation of cross-reactive immunity. In this study...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hou, Jue, Ye, Weijian, Loo, Hooi Linn, Wong, Lan Hiong, Chen, Jianzhu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7545740/
https://ncbi.nlm.nih.gov/pubmed/33101316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.585133
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