Dengue Mosaic Vaccines Enhance Cellular Immunity and Expand the Breadth of Neutralizing Antibody Against All Four Serotypes of Dengue Viruses in Mice

An estimated 400 million people in the world are infected with any of the four types of dengue virus (DENV) annually. The only licensed dengue vaccine cannot effectively prevent infection with all of the four DENVs, especially in those immunologically naïve at baseline. In this study, we explored a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hou, Jue, Shrivastava, Shubham, Fraser, Christopher C., Loo, Hooi Linn, Wong, Lan Hiong, Ho, Victor, Fink, Katja, Ooi, Eng Eong, Chen, Jianzhu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596366/
https://ncbi.nlm.nih.gov/pubmed/31281322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01429
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