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Evolution of Subgenomic RNA Shapes Dengue Virus Adaptation and Epidemiological Fitness

Changes in dengue virus (DENV) genome affect viral fitness both clinically and epidemiologically. Even in the 3′ untranslated region (3′ UTR), mutations could affect subgenomic flaviviral RNA (sfRNA) production and its affinity for host proteins, which are necessary for successful viral replication....

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Finol, Esteban, Ooi, Eng Eong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545344/
https://ncbi.nlm.nih.gov/pubmed/31154208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.05.019
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