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Sequential immunization induces strong and broad immunity against all four dengue virus serotypes

A major challenge in dengue vaccine development is the need to induce immunity against four dengue (DENV) serotypes. Dengvaxia®, the only licensed dengue vaccine, consists of four variant dengue antigens, one for each serotype. Three doses of immunization with the tetravalent vaccine induced only su...

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Detalles Bibliográficos
Publicado en:NPJ Vaccines
Main Authors: Hou, Jue, Shrivastava, Shubham, Loo, Hooi Linn, Wong, Lan Hiong, Ooi, Eng Eong, Chen, Jianzhu
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382454/
https://ncbi.nlm.nih.gov/pubmed/32728482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00216-0
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