Conservation Analysis of Dengue Virus T-cell Epitope-Based Vaccine Candidates Using Peptide Block Entropy

Broad coverage of the pathogen population is particularly important when designing CD8+ T-cell epitope vaccines against viral pathogens. Traditional approaches are based on combinations of highly conserved T-cell epitopes. Peptide block entropy analysis is a novel approach for assembling sets of bro...

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Bibliographic Details
Main Authors: Olsen, Lars Rønn, Zhang, Guang Lan, Keskin, Derin B., Reinherz, Ellis L., Brusic, Vladimir
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2011
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341948/
https://ncbi.nlm.nih.gov/pubmed/22566858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2011.00069
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