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Generation and Characterization of Monoclonal Antibodies against Dengue Virus Type 1 for Epitope Mapping and Serological Detection by Epitope-Based Peptide Antigens

Dengue virus (DEN), the pathogen behind dengue hemorrhagic fever, remains a public health problem in Asia and South America. In this study, monoclonal antibodies (MAbs) against DEN serotype 1 (DEN-1) were generated by fusing NSI/1-Ag4-1 mouse myeloma cells with lymphocytes from BALB/c mice immunized...

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Bibliografiske detaljer
Main Authors: Chen, Yun-Ching, Huang, Hsien-Neng, Lin, Chin-Tarng, Chen, Yi-Fang, King, Chwan-Chuen, Wu, Han-Chung
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865613/
https://ncbi.nlm.nih.gov/pubmed/17287314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00249-06
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