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Structure of CYRI-B (FAM49B), a key regulator of cellular actin assembly

In eukaryotes, numerous fundamental processes are controlled by the WAVE regulatory complex (WRC) that regulates cellular actin polymerization, crucial for cell motility, cell–cell adhesion and epithelial differentiation. Actin assembly is triggered by interaction of the small GTPase Rac1 with CYFIP...

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Dettagli Bibliografici
Pubblicato in:Acta Crystallogr D Struct Biol
Autori principali: Kaplan, Elise, Stone, Rachael, Hume, Peter J., Greene, Nicholas P., Koronakis, Vassilis
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543656/
https://ncbi.nlm.nih.gov/pubmed/33021503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798320010906
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