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Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective
The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram-negative bacteria. Here, we review recent structural and functional data on MacB and its homologs. MacB has a fold that...
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Publicado no: | Front Microbiol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985334/ https://ncbi.nlm.nih.gov/pubmed/29892271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00950 |
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