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Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily

MacB is an ABC transporter that collaborates with the MacA adaptor protein and TolC exit duct to drive efflux of antibiotics and enterotoxin STII out of the bacterial cell. Here we present the structure of ATP-bound MacB and reveal precise molecular details of its mechanism. The MacB transmembrane d...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Crow, Allister, Greene, Nicholas P., Kaplan, Elise, Koronakis, Vassilis
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703307/
https://ncbi.nlm.nih.gov/pubmed/29109272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712153114
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