CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors

Fam49 proteins, now referred to as CYRI (CYFIP-related Rac Interactor), are evolutionarily conserved across many phyla. Their closest relative by amino acid sequence is CYFIP, as both proteins contain a domain of unknown function DUF1394. We recently showed that CYRI and the DUF1394 can mediate bind...

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Detalhes bibliográficos
Publicado no:Commun Integr Biol
Main Authors: Whitelaw, Jamie A., Lilla, Sergio, Paul, Nikki R., Fort, Loic, Zanivan, Sara, Machesky, Laura M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Commentary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682259/
https://ncbi.nlm.nih.gov/pubmed/31413787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420889.2019.1643665
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