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Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function

OBJECTIVES: Respiratory infections in the postacute phase of traumatic brain injury impede optimal recovery and contribute substantially to overall morbidity and mortality. This study investigated bidirectional innate immune responses between the injured brain and lung, using a controlled cortical i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Crit Care Med
Prif Awduron: Doran, Sarah J., Henry, Rebecca J., Shirey, Kari Ann, Barrett, James P., Ritzel, Rodney M., Lai, Wendy, Blanco, Jorge C., Faden, Alan I., Vogel, Stefanie N., Loane, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541908/
https://ncbi.nlm.nih.gov/pubmed/32149839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000004273
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