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Early or Late Bacterial Lung Infection Increases Mortality After Traumatic Brain Injury in Male Mice and Chronically Impairs Monocyte Innate Immune Function

OBJECTIVES: Respiratory infections in the postacute phase of traumatic brain injury impede optimal recovery and contribute substantially to overall morbidity and mortality. This study investigated bidirectional innate immune responses between the injured brain and lung, using a controlled cortical i...

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Vydáno v:Crit Care Med
Hlavní autoři: Doran, Sarah J., Henry, Rebecca J., Shirey, Kari Ann, Barrett, James P., Ritzel, Rodney M., Lai, Wendy, Blanco, Jorge C., Faden, Alan I., Vogel, Stefanie N., Loane, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541908/
https://ncbi.nlm.nih.gov/pubmed/32149839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000004273
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