Interferon-β Plays a Detrimental Role in Experimental Traumatic Brain Injury by Enhancing Neuroinflammation That Drives Chronic Neurodegeneration

DNA damage and type I interferons (IFNs) contribute to inflammatory responses after traumatic brain injury (TBI). TBI-induced activation of microglia and peripherally-derived inflammatory macrophages may lead to tissue damage and neurological deficits. Here, we investigated the role of IFN-β in seco...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Barrett, James P., Henry, Rebecca J., Shirey, Kari Ann, Doran, Sarah J., Makarevich, Oleg D., Ritzel, Rodney M., Meadows, Victoria A., Vogel, Stefanie N., Faden, Alan I., Stoica, Bogdan A., Loane, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083281/
https://ncbi.nlm.nih.gov/pubmed/32029532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2516-19.2020
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