Interferon-β Plays a Detrimental Role in Experimental Traumatic Brain Injury by Enhancing Neuroinflammation That Drives Chronic Neurodegeneration

DNA damage and type I interferons (IFNs) contribute to inflammatory responses after traumatic brain injury (TBI). TBI-induced activation of microglia and peripherally-derived inflammatory macrophages may lead to tissue damage and neurological deficits. Here, we investigated the role of IFN-β in seco...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Barrett, James P., Henry, Rebecca J., Shirey, Kari Ann, Doran, Sarah J., Makarevich, Oleg D., Ritzel, Rodney M., Meadows, Victoria A., Vogel, Stefanie N., Faden, Alan I., Stoica, Bogdan A., Loane, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083281/
https://ncbi.nlm.nih.gov/pubmed/32029532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2516-19.2020
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